Peripheral hypothyroidism and TAFRO syndrome: Particularity of management

TAFRO syndrome is defined by the presence of thrombocytopenia, hydrops, fever, fibrosis, renal dysfunction, and organomegaly can be seen with idiopathic multicentric Castleman disease (iMCD) or as an isolated process without iMCD. The pathophysiology not well understood, but it thought to related hypercytokinemia. Subclinical hypothyroidism may a potential factor in pathogenesis symptomatology elevated vascular endothelial growth (VEGF).There are no clear guidelines for treatment absence definitive diagnosis iMCD, resulting suboptimal management high morbidity. We report case revealed syndrome.